Dynamic Disorder in Single-Enzyme Experiments: Facts and Artifacts
نویسندگان
چکیده
منابع مشابه
Dynamic disorder in single-enzyme experiments: facts and artifacts.
Using a single-molecule fluorescence approach, the time series of catalytic events of an enzymatic reaction can be monitored, yielding a sequence of fluorescent "on"- and "off"-states. An accurate on/off-assignment is complicated by the intrinsic and extrinsic noise in every single-molecule fluorescence experiment. Using simulated data, the performance of the most widely employed binning and th...
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Title Dynamic Disorder in Single-Enzyme Experiments: Facts and Artifacts Author(s) Terentyeva, Tatyana G.; Engelkamp, Hans; Rowan, Alan E.; Komatsuzaki, Tamiki; Hofkens, Johan; Li, Chun-Biu; Blank, Kerstin Citation ACS Nano, 6(1): 346-354 Issue Date 2012-01-24 Doc URL http://hdl.handle.net/2115/51590 Right This document is the Accepted Manuscript version of a Published Work that appeared in fin...
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ژورنال
عنوان ژورنال: ACS Nano
سال: 2011
ISSN: 1936-0851,1936-086X
DOI: 10.1021/nn203669r